Saturday, January 19, 2013

Stroke: An Assault on the Brain

1. Explain what happens to the brain when a stroke occurs.
 A stroke can be described as "brain attack". It occurs when a blood clot blocks an artery or a blood vessel breaks, interrupting blood flow to an area of the brain. When this occurs, the brain cells begin to die and brain damage occurs. When this happens the abilities controlled by that area of the brain are lost. It can be speech, movement and memory. How much does the stroke effect the person depends on few factors, for instants how severe the damage was and where the stroke occurs.

2. Briefly explain the differences between the three different types of strokes.

  •  Ischemic stroke (clots): It occurs as a result of  an obstruction within a blood vessel supplying blood to brain. The  fatty deposits are formed within the blood vessel. This stroke occurs in 87 percent of all cases.
  • Hemorrgaic stroke (bleeds): It results from a weakened vessel that ruptures and bleeds into the surrounding brain. The blood accumulates and compresses the surrounding brain tissue. This type of stroke occurs in 13 percent of all cases.
  • TIA (transient ischemic attack): While transient ischemic attack (TIA) is often labeled “mini-stroke,” it is more accurately characterized as a “warning stroke,” a warning you should take very seriously. It is caused by a clot, but in TIA the clot is temporary and causes no permanent injury of the brain.

3. Identify some of the most common risk factors - in other words, who is most likely to have a stroke?

There are some risk factors that you cannot change like:
  • Age: the older you get the higher chance you have to get a stroke
  • Gender: male are most likely to get a stroke
  • Race: African Americans are most likely to have a stroke than Caucasians
And there are some factors that you can change:
  • High blood pressure - the most dominant stroke risk factor and the easiest to modify is high blood pressure.
  • Smoking - doubles your stroke risk.
  • Weight - Being over-weight predisposes you to high cholesterol, high blood pressure and diabetes, all of which increase stroke risk.
  • Diabetes - makes people susceptible to cardiovascular diseases, which can result in stroke
  • Prior stroke or TIA - increases your risk of having another stroke
  • Heart disease - heart conditions, especially atrial fibrillation (an irregular heart beat), have a greater stroke risk
4. What disabilities can result from a stroke?
Stroke damage in the brain can affect the entire body resulting in mild to severe disabilities. These include paralysis, problems with thinking, problems with speaking, emotional problems, and pain.

5. What is brain plasticity and what does it mean in terms of recovering from a stroke? 


The brain has a remarkable ability to reorganize itself throughout the human life span. The most extraordinary example may be the remodeling of the cerebral cortex after an injury in which a large part of it simply dies. It is not uncommon for stroke patients who have lost the ability to speak or to move a limb to regain function after several weeks of convalescence. How does the brain recover? Using neuro-imaging techniques, Azari and Seitz found a multi-stage process of recovery during which different parts of the brain compensate for the injured region at different times. The results may have implications for therapeutic interventions after a stroke. 


Friday, January 11, 2013

Sperry and Gazzaniga: The Split Brain Study

http://smfuentccc.files.wordpress.com/2012/09/041_splitbrain3.gif1. What does it mean for a person's brain to be "split"?
 It means that they cut off the connection, corpus calosum between the two hemispheres. "Each hemisphere is still able to learn after the split brain operation but one hemisphere has no idea about what the other hemisphere has experienced or learned". The two hemispheres function separately.

2. What was the reason why this procedure was performed on patients?
It began in 1960s to help patients with one kind of epilepsy, because there was no other cure for that at the time.

3. Explain one of the tests Sperry and Gazzaniga performed on these split brain patients.
For one experiment they tested each hemispheres capability to perform simple addition, subtraction, multiplication and division. They showed him examples and presented it to each hemisphere exclusively. Then they showed him a probe. He was given 2 buttons and he was supposed to press a button for "right: or "wrong".
https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEgcQqwC46ewGs8t0Uo8ILyI1dy4TrIZvuQ6Vgn9zGVJbyNzN7RZ5TV2GbTe_Zx2dVf8N1_wX_E4YnO7iVQC1RpVtzXdWUqqClQDb0VpIxVPty1cTdQHqDCF5JhNhjhZAIcP9sshdqnC-l1l/s320/Split+Brain.bmp
4. What were the results of this test?

The results suggested that the left hemisphere is specialized for calculation.

5. What is the reason that these results occurred?
Since the brain is split each hemisphere works separately and each of the two has different "specialization".



6. What is the corpus callosum and what role does it serve in your brain?

The corpus callosum is a thick band of nerve fibers that divides the cerebrum into left and right hemispheres. It connects the left and right sides of the brain allowing for communication between both hemispheres. The corpus callosum transfers motor, sensory, and cognitive information between the brain hemispheres. It serves for eye movements, communication between hemispheres, maintaining the balance of arousal and attention, and also tactile localization.

Sources : http://en.wikipedia.org/wiki/Split-brain , http://www.macalester.edu/academics/psychology/whathap/ubnrp/split_brain/pioneers.html , http://www.nobelprize.org/educational/medicine/split-brain/background.html